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Prior AICAR induces elevated glucose uptake concomitant with greater γ3-AMPK activation and reduced membrane cholesterol in skeletal muscle from 26-month-old rats

Attenuated skeletal muscle glucose uptake (GU) has been observed with advancing age. It is important to elucidate the mechanisms linked to interventions that oppose this detrimental outcome. Earlier research using young rodents and (or) cultured myocytes reported that treatment with 5-aminoimidazole...

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Detalles Bibliográficos
Autores principales: Wang, Haiyan, Zheng, Amy, Arias, Edward B., Cartee, Gregory D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648397/
https://www.ncbi.nlm.nih.gov/pubmed/36381195
http://dx.doi.org/10.1139/facets-2021-0166