Replication Stress Defines Distinct Molecular Subtypes Across Cancers

Endogenous replication stress is a major driver of genomic instability. Current assessments of replication stress are low throughput precluding its comprehensive assessment across tumors. Here we develop and validate a transcriptional profile of replication stress by leveraging established cellular...

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Detalles Bibliográficos
Autores principales: Takahashi, Nobuyuki, Kim, Sehyun, Schultz, Christopher W., Rajapakse, Vinodh N., Zhang, Yang, Redon, Christophe E., Fu, Haiqing, Pongor, Lorinc, Kumar, Suresh, Pommier, Yves, Aladjem, Mirit I., Thomas, Anish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648410/
https://www.ncbi.nlm.nih.gov/pubmed/36381660
http://dx.doi.org/10.1158/2767-9764.CRC-22-0168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648410/
https://www.ncbi.nlm.nih.gov/pubmed/36381660
http://dx.doi.org/10.1158/2767-9764.CRC-22-0168

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