Cargando…

SLFN11 Negatively Regulates Noncanonical NFκB Signaling to Promote Glioblastoma Progression

Glioblastoma (GBM) is an aggressive and incurable brain tumor in nearly all instances, whose disease progression is driven in part by the glioma stem cell (GSC) subpopulation. Here, we explored the effects of Schlafen family member 11 (SLFN11) in the molecular, cellular, and tumor biology of GBM. CR...

Descripción completa

Detalles Bibliográficos
Autores principales: Fischietti, Mariafausta, Eckerdt, Frank, Perez, Ricardo E., Guillen Magaña, Jamie N., Mazewski, Candice, Ho, Sang, Gonzalez, Christopher, Streich, Lukas D., Beauchamp, Elspeth M., Heimberger, Amy B., Baran, Aneta H., Yue, Feng, James, C. David, Platanias, Leonidas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648417/
https://www.ncbi.nlm.nih.gov/pubmed/36382088
http://dx.doi.org/10.1158/2767-9764.CRC-22-0192