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Bintrafusp Alfa, an Anti-PD-L1:TGFβ Trap Fusion Protein, in Patients with ctDNA-positive, Liver-limited Metastatic Colorectal Cancer

Identification of circulating tumor DNA (ctDNA) following curative intent therapies is a surrogate for microscopic residual disease for patients with metastatic colorectal cancer (mCRC). Preclinically, in micrometastatic microsatellite stable (MSS) colorectal cancer, increased TGFβ signaling results...

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Detalles Bibliográficos
Autores principales: Morris, Van K., Overman, Michael J., Lam, Michael, Parseghian, Christine M., Johnson, Benny, Dasari, Arvind, Raghav, Kanwal, Kee, Bryan K., Huey, Ryan, Wolff, Robert A., Shen, John Paul, Li, June, Zorrilla, Isabel, Tzeng, Ching-Wei D., Tran Cao, Hop S., Chun, Yun Shin, Newhook, Timothy E., Vauthey, Nicolas, Duose, Dzifa, Luthra, Raja, Haymaker, Cara, Kopetz, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648419/
https://www.ncbi.nlm.nih.gov/pubmed/36382087
http://dx.doi.org/10.1158/2767-9764.CRC-22-0194