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Bintrafusp Alfa, an Anti-PD-L1:TGFβ Trap Fusion Protein, in Patients with ctDNA-positive, Liver-limited Metastatic Colorectal Cancer
Identification of circulating tumor DNA (ctDNA) following curative intent therapies is a surrogate for microscopic residual disease for patients with metastatic colorectal cancer (mCRC). Preclinically, in micrometastatic microsatellite stable (MSS) colorectal cancer, increased TGFβ signaling results...
Autores principales: | Morris, Van K., Overman, Michael J., Lam, Michael, Parseghian, Christine M., Johnson, Benny, Dasari, Arvind, Raghav, Kanwal, Kee, Bryan K., Huey, Ryan, Wolff, Robert A., Shen, John Paul, Li, June, Zorrilla, Isabel, Tzeng, Ching-Wei D., Tran Cao, Hop S., Chun, Yun Shin, Newhook, Timothy E., Vauthey, Nicolas, Duose, Dzifa, Luthra, Raja, Haymaker, Cara, Kopetz, Scott |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648419/ https://www.ncbi.nlm.nih.gov/pubmed/36382087 http://dx.doi.org/10.1158/2767-9764.CRC-22-0194 |
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