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Calpain-mediated proteolysis as driver and modulator of polyglutamine toxicity
Among posttranslational modifications, directed proteolytic processes have the strongest impact on protein integrity. They are executed by a variety of cellular machineries and lead to a wide range of molecular consequences. Compared to other forms of proteolytic enzymes, the class of calcium-activa...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648470/ https://www.ncbi.nlm.nih.gov/pubmed/36385755 http://dx.doi.org/10.3389/fnmol.2022.1020104 |