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Calpain-mediated proteolysis as driver and modulator of polyglutamine toxicity

Among posttranslational modifications, directed proteolytic processes have the strongest impact on protein integrity. They are executed by a variety of cellular machineries and lead to a wide range of molecular consequences. Compared to other forms of proteolytic enzymes, the class of calcium-activa...

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Detalles Bibliográficos
Autores principales: Incebacak Eltemur, Rana Dilara, Nguyen, Huu Phuc, Weber, Jonasz Jeremiasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648470/
https://www.ncbi.nlm.nih.gov/pubmed/36385755
http://dx.doi.org/10.3389/fnmol.2022.1020104