Cargando…
Calpain-mediated proteolysis as driver and modulator of polyglutamine toxicity
Among posttranslational modifications, directed proteolytic processes have the strongest impact on protein integrity. They are executed by a variety of cellular machineries and lead to a wide range of molecular consequences. Compared to other forms of proteolytic enzymes, the class of calcium-activa...
Autores principales: | Incebacak Eltemur, Rana Dilara, Nguyen, Huu Phuc, Weber, Jonasz Jeremiasz |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648470/ https://www.ncbi.nlm.nih.gov/pubmed/36385755 http://dx.doi.org/10.3389/fnmol.2022.1020104 |
Ejemplares similares
-
Editorial: The role of posttranslational modifications in polyglutamine diseases
por: Weber, Jonasz Jeremiasz, et al.
Publicado: (2023) -
Calpains as novel players in the molecular pathogenesis of spinocerebellar ataxia type 17
por: Weber, Jonasz Jeremiasz, et al.
Publicado: (2022) -
Implications of specific lysine residues within ataxin-3 for the molecular pathogenesis of Machado-Joseph disease
por: Pereira Sena, Priscila, et al.
Publicado: (2023) -
Killing Two Angry Birds with One Stone: Autophagy Activation by Inhibiting Calpains in Neurodegenerative Diseases and Beyond
por: Weber, Jonasz Jeremiasz, et al.
Publicado: (2019) -
KPNB1 modulates the Machado–Joseph disease protein ataxin-3 through activation of the mitochondrial protease CLPP
por: Abeditashi, Mahkameh, et al.
Publicado: (2022)