Catch-enrich-release approach for amine-containing natural products

Amine-containing natural products are an important class of therapeutic compounds. Herein, we report a chemoselective approach to catch and enrich amine-containing natural products, and release them as underivatized compounds. The strategy exploits the selectivity of the enzyme legumain for the spec...

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Detalles Bibliográficos
Autores principales: Müller, Michelle Jessy, Dorst, Andrea, Paulus, Constanze, Khan, Imran, Sieber, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648515/
https://www.ncbi.nlm.nih.gov/pubmed/36264220
http://dx.doi.org/10.1039/d2cc04905h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648515/
https://www.ncbi.nlm.nih.gov/pubmed/36264220
http://dx.doi.org/10.1039/d2cc04905h

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