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Catch-enrich-release approach for amine-containing natural products
Amine-containing natural products are an important class of therapeutic compounds. Herein, we report a chemoselective approach to catch and enrich amine-containing natural products, and release them as underivatized compounds. The strategy exploits the selectivity of the enzyme legumain for the spec...
Autores principales: | Müller, Michelle Jessy, Dorst, Andrea, Paulus, Constanze, Khan, Imran, Sieber, Simon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648515/ https://www.ncbi.nlm.nih.gov/pubmed/36264220 http://dx.doi.org/10.1039/d2cc04905h |
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