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Mitochondrial aggregation caused by cytochalasin B compromises the efficiency and safety of three-parent embryo

It is widely accepted that cytochalasin B (CB) is required in enucleation of the oocyte in order to stabilize the cytoplasm. However, CB treatment results in the uneven distribution of mitochondria, with aggregation towards the nucleus, which might compromise the efficiency and safety of a three-par...

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Detalles Bibliográficos
Autores principales: Li, Ying, Shi, Sanbao, Yuan, Jin, Xiao, Xi, Ji, Dongmei, Pan, Jianxin, Min, Zhunyuan, Wang, Hao, Sha, Hongying, Ji, Yazhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648687/
https://www.ncbi.nlm.nih.gov/pubmed/36264122
http://dx.doi.org/10.1093/molehr/gaac036