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Hyperbaric oxygen protects HT22 cells and PC12 cells from damage caused by oxygen-glucose deprivation/reperfusion via the inhibition of Nrf2/System Xc-/GPX4 axis-mediated ferroptosis

This study was to investigate the protective effect of hyperbaric oxygen (HBO) on HT22 and PC12 cell damage caused by oxygen-glucose deprivation/reperfusion-induced ferroptosis. A 2-h oxygen-glucose deprivation and 24-h reperfusion model on HT22 and PC12 cells was used to simulate cerebral ischemia-...

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Detalles Bibliográficos
Autores principales: Chen, Chunxia, Chen, Wan, Zhou, Xing, Li, Yaoxuan, Pan, Xiaorong, Chen, Xiaoyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648730/
https://www.ncbi.nlm.nih.gov/pubmed/36355759
http://dx.doi.org/10.1371/journal.pone.0276083