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Parthenolide targets NF-κB (P50) to inhibit HIF-1α-mediated metabolic reprogramming of HCC

We focus on investigating the role of Parthenolide (Par), a small sesquiterpenoid molecule, in hepatocellular carcinoma (HCC) and its effective target. Highly-metastatic HCC cells, MHCC97-H, were divided into the DMSO and the Par groups, of which the Par group was intervened at 5 and 10 mg/L doses....

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Detalles Bibliográficos
Autores principales: Liu, Xiaorong, Gao, Zhaofeng, Wang, Xiaoguang, Shen, Yiyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648796/
https://www.ncbi.nlm.nih.gov/pubmed/36260873
http://dx.doi.org/10.18632/aging.204339