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Downregulation of senescence-associated secretory phenotype by knockdown of secreted frizzled-related protein 4 contributes to the prevention of skin aging

There is growing evidence that the appearance and texture of the skin that is altered during the aging process are considerably enhanced by the accumulation of senescent dermal fibroblasts. These senescent cells magnify aging via an inflammatory, histolytic, and senescence-associated secretory pheno...

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Detalles Bibliográficos
Autores principales: Takaya, Kento, Asou, Toru, Kishi, Kazuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648805/
https://www.ncbi.nlm.nih.gov/pubmed/36084952
http://dx.doi.org/10.18632/aging.204273