Crosstalk between age accumulated DNA-damage and the SIRT1-AKT-GSK3ß axis in urine derived renal progenitor cells

The aging process is manifested by a multitude of inter-linked biological processes. These processes contribute to genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, de-regulated nutrient-sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustio...

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Detalles Bibliográficos
Autores principales: Erichsen, Lars, Adjaye, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648809/
https://www.ncbi.nlm.nih.gov/pubmed/36170022
http://dx.doi.org/10.18632/aging.204300

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648809/
https://www.ncbi.nlm.nih.gov/pubmed/36170022
http://dx.doi.org/10.18632/aging.204300

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