Combining stem cell rejuvenation and senescence targeting to synergistically extend lifespan

Why biological age is a major risk factor for many of the most important human diseases remains mysterious. We know that as organisms age, stem cell pools are exhausted while senescent cells progressively accumulate. Independently, induction of pluripotency via expression of Yamanaka factors (Oct4,...

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Detalles Bibliográficos
Autores principales: Kaur, Prameet, Otgonbaatar, Agimaa, Ramamoorthy, Anupriya, Chua, Ellora Hui Zhen, Harmston, Nathan, Gruber, Jan, Tolwinski, Nicholas S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648810/
https://www.ncbi.nlm.nih.gov/pubmed/36287172
http://dx.doi.org/10.18632/aging.204347

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648810/
https://www.ncbi.nlm.nih.gov/pubmed/36287172
http://dx.doi.org/10.18632/aging.204347

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