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Exon-dependent transcriptional adaptation by exon-junction complex proteins Y14/RNP-4 and MAGOH/MAG-1 in Caenorhabditis elegans

Transcriptional adaptation is a powerful gene regulation mechanism that can increase genetic robustness. Transcriptional adaptation occurs when a gene is mutated and is mediated by the mutant RNA, rather than by protein feedback loops. We show here that transcriptional adaptation occurs in the C. el...

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Detalles Bibliográficos
Autores principales: Fernandez-Abascal, Jesus, Wang, Lei, Graziano, Bianca, Johnson, Christina K., Bianchi, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648848/
https://www.ncbi.nlm.nih.gov/pubmed/36315586
http://dx.doi.org/10.1371/journal.pgen.1010488