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Getting higher on rugged landscapes: Inversion mutations open access to fitter adaptive peaks in NK fitness landscapes
Molecular evolution is often conceptualised as adaptive walks on rugged fitness landscapes, driven by mutations and constrained by incremental fitness selection. It is well known that epistasis shapes the ruggedness of the landscape’s surface, outlining their topography (with high-fitness peaks sepa...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648849/ https://www.ncbi.nlm.nih.gov/pubmed/36315581 http://dx.doi.org/10.1371/journal.pcbi.1010647 |