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Getting higher on rugged landscapes: Inversion mutations open access to fitter adaptive peaks in NK fitness landscapes

Molecular evolution is often conceptualised as adaptive walks on rugged fitness landscapes, driven by mutations and constrained by incremental fitness selection. It is well known that epistasis shapes the ruggedness of the landscape’s surface, outlining their topography (with high-fitness peaks sepa...

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Detalles Bibliográficos
Autores principales: Trujillo, Leonardo, Banse, Paul, Beslon, Guillaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648849/
https://www.ncbi.nlm.nih.gov/pubmed/36315581
http://dx.doi.org/10.1371/journal.pcbi.1010647

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