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SRSF10 is essential for progenitor spermatogonia expansion by regulating alternative splicing

Alternative splicing expands the transcriptome and proteome complexity and plays essential roles in tissue development and human diseases. However, how alternative splicing regulates spermatogenesis remains largely unknown. Here, using a germ cell-specific knockout mouse model, we demonstrated that...

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Detalles Bibliográficos
Autores principales: Liu, Wenbo, Lu, Xukun, Zhao, Zheng-Hui, SU, Ruibao, Li, Qian-Nan Li, Xue, Yue, Gao, Zheng, Sun, Si-Min Sun, Lei, Wen-Long, Li, Lei, An, Geng, Liu, Hanyan, Han, Zhiming, Ouyang, Ying-Chun, Hou, Yi, Wang, Zhen-Bo, Sun, Qing-Yuan, Liu, Jianqiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648972/
https://www.ncbi.nlm.nih.gov/pubmed/36355419
http://dx.doi.org/10.7554/eLife.78211