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IFN-β mediates the anti-osteoclastic effect of bisphosphonates and dexamethasone

Zoledronic acid (Zol) is a potent bisphosphonate that inhibits the differentiation of monocytes into osteoclasts. It is often used in combination with dexamethasone (Dex), a glucocorticoid that promotes the resolution of inflammation, to treat malignant diseases, such as multiple myeloma. This treat...

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Detalles Bibliográficos
Autores principales: Kalkar, Prajakta, Cohen, Gal, Tamari, Tal, Schif-Zuck, Sagie, Zigdon-Giladi, Hadar, Ariel, Amiram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648992/
https://www.ncbi.nlm.nih.gov/pubmed/36386129
http://dx.doi.org/10.3389/fphar.2022.1002550