2,4-Dihydroxycinnamic acid as spike ACE2 inhibitor and apigenin as RdRp inhibitor in Nimbamritadi Panchatiktam Kashayam against COVID-19: an in silico and in vitro approach

Nimbamritadi Panchatiktam Kashayam (NPK) is an ayurvedic formulation composed of ingredients with potent anti-viral activities. We studied the interaction energy of 144 phytoconstituents present in NPK against spike receptor-binding domain (RBD) complexed with ACE2 protein (PDB ID: 6LZG) and RNA-dep...

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Detalles Bibliográficos
Autores principales: Murali, Maneesha, Nair, Bhagyalakshmi, Vishnu, V. R., Aneesh, T. P., Nath, Lekshmi R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648999/
https://www.ncbi.nlm.nih.gov/pubmed/36357813
http://dx.doi.org/10.1007/s11030-022-10552-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648999/
https://www.ncbi.nlm.nih.gov/pubmed/36357813
http://dx.doi.org/10.1007/s11030-022-10552-z

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