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Oral bioavailability of microdoses and therapeutic doses of midazolam as a 2-dimensionally printed orodispersible film in healthy volunteers

PURPOSE: The use of two-dimensional (2D) printing technologies of drugs on orodispersible films (ODF) can promote dose individualization and facilitate drug delivery in vulnerable patients, including children. We investigated midazolam pharmacokinetics after the administration of 2D-printed ODF. MET...

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Detalles Bibliográficos
Autores principales: Breithaupt, Mareile H., Krohmer, Evelyn, Taylor, Lenka, Koerner, Eva, Hoppe-Tichy, Torsten, Burhenne, Juergen, Foerster, Kathrin I., Dachtler, Markus, Huber, Gerald, Venkatesh, Rakesh, Eggenreich, Karin, Czock, David, Mikus, Gerd, Blank, Antje, Haefeli, Walter E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9649511/
https://www.ncbi.nlm.nih.gov/pubmed/36258053
http://dx.doi.org/10.1007/s00228-022-03406-y