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Oral bioavailability of microdoses and therapeutic doses of midazolam as a 2-dimensionally printed orodispersible film in healthy volunteers
PURPOSE: The use of two-dimensional (2D) printing technologies of drugs on orodispersible films (ODF) can promote dose individualization and facilitate drug delivery in vulnerable patients, including children. We investigated midazolam pharmacokinetics after the administration of 2D-printed ODF. MET...
Autores principales: | Breithaupt, Mareile H., Krohmer, Evelyn, Taylor, Lenka, Koerner, Eva, Hoppe-Tichy, Torsten, Burhenne, Juergen, Foerster, Kathrin I., Dachtler, Markus, Huber, Gerald, Venkatesh, Rakesh, Eggenreich, Karin, Czock, David, Mikus, Gerd, Blank, Antje, Haefeli, Walter E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9649511/ https://www.ncbi.nlm.nih.gov/pubmed/36258053 http://dx.doi.org/10.1007/s00228-022-03406-y |
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