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Riboflavin depletion promotes longevity and metabolic hormesis in Caenorhabditis elegans

Riboflavin is an essential cofactor in many enzymatic processes and in the production of flavin adenine dinucleotide (FAD). Here, we report that the partial depletion of riboflavin through knockdown of the C. elegans riboflavin transporter 1 (rft‐1) promotes metabolic health by reducing intracellula...

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Detalles Bibliográficos
Autores principales: Yerevanian, Armen, Murphy, Luke M., Emans, Sinclair, Zhou, Yifei, Ahsan, Fasih M., Baker, Daniel, Li, Sainan, Adedoja, Adebanjo, Cedillo, Lucydalila, Stuhr, Nicole L., Gnanatheepam, Einstein, Dao, Khoi, Jain, Mohit, Curran, Sean P., Georgakoudi, Irene, Soukas, Alexander A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9649603/
https://www.ncbi.nlm.nih.gov/pubmed/36181246
http://dx.doi.org/10.1111/acel.13718