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Exaggerated hypoxic vascular breakdown in aged brain due to reduced microglial vasculo‐protection
In a recent study of young mice, we showed that chronic mild hypoxia (CMH, 8% O(2)) triggers transient blood–brain barrier (BBB) disruption, and that microglia play an important vasculo‐protective function in maintaining BBB integrity. As hypoxia is a common component of many age‐related diseases, h...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9649604/ https://www.ncbi.nlm.nih.gov/pubmed/36130175 http://dx.doi.org/10.1111/acel.13720 |