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Muscular Swedish mutant APP-to-Brain axis in the development of Alzheimer’s disease
Alzheimer’s disease (AD) is the most common form of dementia. Notably, patients with AD often suffer from severe sarcopenia. However, their direct link and relationship remain poorly understood. Here, we generated a mouse line, TgAPP(swe)(HSA), by crossing LSL (LoxP-STOP-LoxP)-APP(swe) with HSA-Cre...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9649614/ https://www.ncbi.nlm.nih.gov/pubmed/36357367 http://dx.doi.org/10.1038/s41419-022-05378-4 |