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Muscular Swedish mutant APP-to-Brain axis in the development of Alzheimer’s disease

Alzheimer’s disease (AD) is the most common form of dementia. Notably, patients with AD often suffer from severe sarcopenia. However, their direct link and relationship remain poorly understood. Here, we generated a mouse line, TgAPP(swe)(HSA), by crossing LSL (LoxP-STOP-LoxP)-APP(swe) with HSA-Cre...

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Detalles Bibliográficos
Autores principales:	Pan, Jin-Xiu, Lee, Daehoon, Sun, Dong, Zhao, Kai, Xiong, Lei, Guo, Hao-Han, Ren, Xiao, Chen, Peng, Lopez de Boer, Raquel, Lu, Yuyi, Lin, Helena, Mei, Lin, Xiong, Wen-Cheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9649614/ https://www.ncbi.nlm.nih.gov/pubmed/36357367 http://dx.doi.org/10.1038/s41419-022-05378-4

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