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The antipsychotic drug sulpiride in the ventral pallidum paradoxically impairs learning and induces place preference

Sulpiride, as a D2-like dopamine (DA) receptor (D2R) antagonist, is an important antipsychotic drug in the treatment of schizophrenia. Recently, we have shown that the activation of D2Rs in the ventral pallidum (VP) modulates the activity of the ventral tegmental area (VTA) DAergic neurons. Accordin...

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Detalles Bibliográficos
Autores principales: Dusa, Daniella, Ollmann, Tamás, Kállai, Veronika, Lénárd, László, Kertes, Erika, Berta, Beáta, Szabó, Ádám, László, Kristóf, Gálosi, Rita, Zagoracz, Olga, Karádi, Zoltán, Péczely, László
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9649625/
https://www.ncbi.nlm.nih.gov/pubmed/36357539
http://dx.doi.org/10.1038/s41598-022-23450-z