Magic-angle-spinning NMR structure of the kinesin-1 motor domain assembled with microtubules reveals the elusive neck linker orientation

Microtubules (MTs) and their associated proteins play essential roles in maintaining cell structure, organelle transport, cell motility, and cell division. Two motors, kinesin and cytoplasmic dynein link the MT network to transported cargos using ATP for force generation. Here, we report an all-atom...

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Detalles Bibliográficos
Autores principales: Zhang, Chunting, Guo, Changmiao, Russell, Ryan W., Quinn, Caitlin M., Li, Mingyue, Williams, John C., Gronenborn, Angela M., Polenova, Tatyana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9649657/
https://www.ncbi.nlm.nih.gov/pubmed/36357375
http://dx.doi.org/10.1038/s41467-022-34026-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9649657/
https://www.ncbi.nlm.nih.gov/pubmed/36357375
http://dx.doi.org/10.1038/s41467-022-34026-w

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