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Identification and in silico analysis of noval alteration Arg420Gly in KIT proto oncogene among acute myeloid leukemia patients

A number of studies have reported frequent incidence of c-kit gene mutations in association with core binding factor acute myeloid leukemia (CBF-AML). These genetic changes have become important prognostic predictors in patients with abnormal karyotype. Aim of this study was the detection of nucleot...

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Detalles Bibliográficos
Autores principales: Akram, Afia Muhammad, Hassan, Mubashir, Chaudhary, Asma, Hayat, Sikandar, Ali, Qurban, Hussain, Taha, Zafar, Amjad, Javed, Muhammad Arshad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9649709/
https://www.ncbi.nlm.nih.gov/pubmed/36357474
http://dx.doi.org/10.1038/s41598-022-23934-y