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Automated preclinical detection of mechanical pain hypersensitivity and analgesia

The lack of sensitive and robust behavioral assessments of pain in preclinical models has been a major limitation for both pain research and the development of novel analgesics. Here, we demonstrate a novel data acquisition and analysis platform that provides automated, quantitative, and objective m...

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Detalles Bibliográficos
Autores principales: Zhang, Zihe, Roberson, David P., Kotoda, Masakazu, Boivin, Bruno, Bohnslav, James P., González-Cano, Rafael, Yarmolinsky, David A., Turnes, Bruna Lenfers, Wimalasena, Nivanthika K., Neufeld, Shay Q., Barrett, Lee B., Quintão, Nara L. M., Fattori, Victor, Taub, Daniel G., Wiltschko, Alexander B., Andrews, Nick A., Harvey, Christopher D., Datta, Sandeep Robert, Woolf, Clifford J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9649838/
https://www.ncbi.nlm.nih.gov/pubmed/35543646
http://dx.doi.org/10.1097/j.pain.0000000000002680