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Dose-related shifts in proteome and function of extracellular vesicles secreted by fetal neural stem cells following chronic alcohol exposure

Accumulating evidence indicates that extracellular vesicles (EVs) mediate endocrine functions and also pathogenic effects of neurodevelopmental perturbagens like ethanol. We performed mass-spectrometry on EVs secreted by fetal murine cerebral cortical neural stem cells (NSCs), cultured ex-vivo as se...

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Detalles Bibliográficos
Autores principales: Chung, Dae D., Pinson, Marisa R., Mahnke, Amanda H., Salem, Nihal A., Le, Khang T., Payne, Elizabeth A., Lehman, Tenley E., Weintraub, Susan T., Miranda, Rajesh C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9649983/
https://www.ncbi.nlm.nih.gov/pubmed/36387439
http://dx.doi.org/10.1016/j.heliyon.2022.e11348