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Organelle bottlenecks facilitate evolvability by traversing heteroplasmic fitness valleys

Bioenergetic organelles—mitochondria and plastids—retain their own genomes (mtDNA and ptDNA), and these organelle DNA (oDNA) molecules are vital for eukaryotic life. Like all genomes, oDNA must be able to evolve to suit new environmental challenges. However, mixed oDNA populations in cells can chall...

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Detalles Bibliográficos
Autores principales: Radzvilavicius, Arunas L., Johnston, Iain G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9650085/
https://www.ncbi.nlm.nih.gov/pubmed/36386853
http://dx.doi.org/10.3389/fgene.2022.974472