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Organelle bottlenecks facilitate evolvability by traversing heteroplasmic fitness valleys
Bioenergetic organelles—mitochondria and plastids—retain their own genomes (mtDNA and ptDNA), and these organelle DNA (oDNA) molecules are vital for eukaryotic life. Like all genomes, oDNA must be able to evolve to suit new environmental challenges. However, mixed oDNA populations in cells can chall...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9650085/ https://www.ncbi.nlm.nih.gov/pubmed/36386853 http://dx.doi.org/10.3389/fgene.2022.974472 |