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Brain derived neurotrophic factor/tropomyosin related kinase B signaling impacts diaphragm neuromuscular transmission in a novel rat chemogenetic model

The neuromuscular junction (NMJ) mediates neural control of skeletal muscle fibers. Neurotrophic signaling, specifically brain derived neurotrophic factor (BDNF) acting through its high-affinity tropomyosin related kinase B (TrkB) receptor is known to improve neuromuscular transmission. BDNF/TrkB si...

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Detalles Bibliográficos
Autores principales: Fogarty, Matthew J., Khurram, Obaid U., Mantilla, Carlos B., Sieck, Gary C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9650098/
https://www.ncbi.nlm.nih.gov/pubmed/36385943
http://dx.doi.org/10.3389/fncel.2022.1025463