Cargando…

Synthetic gene circuits for cell state detection and protein tuning in human pluripotent stem cells

During development, cell state transitions are coordinated through changes in the identity of molecular regulators in a cell type‐ and dose‐specific manner. The ability to rationally engineer such transitions in human pluripotent stem cells (hPSC) will enable numerous applications in regenerative me...

Descripción completa

Detalles Bibliográficos
Autores principales: Prochazka, Laura, Michaels, Yale S, Lau, Charles, Jones, Ross D, Siu, Mona, Yin, Ting, Wu, Diana, Jang, Esther, Vázquez‐Cantú, Mercedes, Gilbert, Penney M, Kaul, Himanshu, Benenson, Yaakov, Zandstra, Peter W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9650275/
https://www.ncbi.nlm.nih.gov/pubmed/36366891
http://dx.doi.org/10.15252/msb.202110886