Advances in antitumor research of CA-4 analogs carrying quinoline scaffold

Combretastatin A-4 (CA-4) is a potent inhibitor of tubulin polymerization and a colchicine binding site inhibitor (CBSI). The structure-activity relationship study of CA-4 showed that the cis double bond configuration and the 3,4,5-trimethoxy group on the A ring were important factors to maintain th...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Chao, Chang, Jing, Yang, Shanbo, Shi, Lingyu, Zhang, Yujing, Liu, Wenjing, Meng, Jingsen, Zeng, Jun, Zhang, Renshuai, Xing, Dongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9650302/
https://www.ncbi.nlm.nih.gov/pubmed/36385996
http://dx.doi.org/10.3389/fchem.2022.1040333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9650302/
https://www.ncbi.nlm.nih.gov/pubmed/36385996
http://dx.doi.org/10.3389/fchem.2022.1040333

Ejemplares similares