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Increased pain unpleasantness and pain-related fMRI activation in the periaqueductal gray in Alzheimer's disease
BACKGROUND: Pain continues to be underrecognized and undertreated in people with Alzheimer's disease (AD). The periaqueductal gray (PAG) is essential to pain processing and modulation yet is damaged by AD. While evidence exists of altered neural processing of pain in AD, there has not been a fo...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9650512/ https://www.ncbi.nlm.nih.gov/pubmed/36387417 http://dx.doi.org/10.3389/fpain.2022.914473 |