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Increased pain unpleasantness and pain-related fMRI activation in the periaqueductal gray in Alzheimer's disease

BACKGROUND: Pain continues to be underrecognized and undertreated in people with Alzheimer's disease (AD). The periaqueductal gray (PAG) is essential to pain processing and modulation yet is damaged by AD. While evidence exists of altered neural processing of pain in AD, there has not been a fo...

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Detalles Bibliográficos
Autores principales: Anderson, Alison R., Monroe, Todd B., Dietrich, Mary S., Bruehl, Stephen P., Iversen, W. Larkin, Cowan, Ronald L., Failla, Michelle D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9650512/
https://www.ncbi.nlm.nih.gov/pubmed/36387417
http://dx.doi.org/10.3389/fpain.2022.914473