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Eldecalcitol prevents muscle loss by suppressing PI3K/AKT/FOXOs pathway in orchiectomized mice

Elderly male patients are susceptible to develop osteoporosis and sarcopenia, especially those with fragility fractures, hypogonadism, and prostate cancer with androgen deprivation therapy. However, at present, very few treatments are available for men with sarcopenia. Previous preclinical studies i...

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Detalles Bibliográficos
Autores principales: Zhang, Haichao, Ke, Zheng, Dong, Shuangshuang, Du, Yanping, Tang, Wenjing, Chen, Minmin, Yu, Weijia, Cheng, Qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9650589/
https://www.ncbi.nlm.nih.gov/pubmed/36386197
http://dx.doi.org/10.3389/fphar.2022.1018480