Wnt-5a induces the conversion of silent to functional synapses in the hippocampus

Synapse unsilencing is an essential mechanism for experience-dependent plasticity. Here, we showed that the application of the ligand Wnt-5a converts glutamatergic silent synapses into functional ones by increasing both α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) and N-methyl-D-aspa...

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Detalles Bibliográficos
Autores principales: Álvarez-Ferradas, Carla, Wellmann, Mario, Morales, Koyam, Fuenzalida, Marco, Cerpa, Waldo, Inestrosa, Nibaldo C., Bonansco, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9650636/
https://www.ncbi.nlm.nih.gov/pubmed/36385757
http://dx.doi.org/10.3389/fnmol.2022.1024034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9650636/
https://www.ncbi.nlm.nih.gov/pubmed/36385757
http://dx.doi.org/10.3389/fnmol.2022.1024034

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