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Time-of-day dependent effects of midazolam administration on myocardial injury in non-cardiac surgery

BACKGROUND: Animal studies have shown that midazolam can increase vulnerability to cardiac ischemia, potentially via circadian-mediated mechanisms. We hypothesized that perioperative midazolam administration is associated with an increased incidence of myocardial injury in patients undergoing non-ca...

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Detalles Bibliográficos
Autores principales: Prin, Meghan, Pattee, Jack, Douin, David J., Scott, Benjamin K., Ginde, Adit A., Eckle, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9650651/
https://www.ncbi.nlm.nih.gov/pubmed/36386382
http://dx.doi.org/10.3389/fcvm.2022.982209