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Genomic landscape of the immunogenicity regulation in skin melanomas with diverse tumor mutation burden

Skin melanoma cells are tightly interconnected with their tumor microenvironment (TME), which influences their initiation, progression, and sensitivity/resistance to therapeutic interventions. An immune-active TME favors patient response to immune checkpoint inhibition (ICI), but not all patients re...

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Detalles Bibliográficos
Autores principales: Georgoulias, George, Zaravinos, Apostolos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9650672/
https://www.ncbi.nlm.nih.gov/pubmed/36389735
http://dx.doi.org/10.3389/fimmu.2022.1006665