Positive selection-driven fixation of a hominin-specific amino acid mutation related to dephosphorylation in IRF9

The arms race between humans and pathogens drives the evolution of the human genome. It is thus expected that genes from the interferon-regulatory factors family (IRFs), a critical family for anti-viral immune response, should be undergoing episodes of positive selection. Herein, we tested this hypo...

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Detalles Bibliográficos
Autores principales: Chen, Jianhai, He, Xuefei, Jakovlić, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9650800/
https://www.ncbi.nlm.nih.gov/pubmed/36357830
http://dx.doi.org/10.1186/s12862-022-02088-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9650800/
https://www.ncbi.nlm.nih.gov/pubmed/36357830
http://dx.doi.org/10.1186/s12862-022-02088-5

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