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Positive selection-driven fixation of a hominin-specific amino acid mutation related to dephosphorylation in IRF9
The arms race between humans and pathogens drives the evolution of the human genome. It is thus expected that genes from the interferon-regulatory factors family (IRFs), a critical family for anti-viral immune response, should be undergoing episodes of positive selection. Herein, we tested this hypo...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9650800/ https://www.ncbi.nlm.nih.gov/pubmed/36357830 http://dx.doi.org/10.1186/s12862-022-02088-5 |