Multiomics analyses reveals Anaplasma phagocytophilum Ats-1 induces anti-apoptosis and energy metabolism by upregulating the respiratory chain-mPTP axis in eukaryotic mitochondria

BACKGROUND: Anaplasma translocated substrate 1 (Ats-1) is an effector of type 4 secretory systems (T4SS) and the main virulence factor of Anaplasma phagocytophilum. Ats-1 is involved in the regulation of host cell biological processes, but the specific molecular mechanism of its action is unclear. R...

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Detalles Bibliográficos
Autores principales: Li, Ruirui, Ma, Zhongchen, Zheng, Wei, Wang, Zhen, Yi, Jihai, Xiao, Yangyang, Wang, Yong, Chen, Chuangfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9650841/
https://www.ncbi.nlm.nih.gov/pubmed/36357826
http://dx.doi.org/10.1186/s12866-022-02668-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9650841/
https://www.ncbi.nlm.nih.gov/pubmed/36357826
http://dx.doi.org/10.1186/s12866-022-02668-x

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