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Tuning gradient boosting for imbalanced bioassay modelling with custom loss functions
While in the last years there has been a dramatic increase in the number of available bioassay datasets, many of them suffer from extremely imbalanced distribution between active and inactive compounds. Thus, there is an urgent need for novel approaches to tackle class imbalance in drug discovery. I...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9650867/ https://www.ncbi.nlm.nih.gov/pubmed/36357942 http://dx.doi.org/10.1186/s13321-022-00657-w |