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Systematic characterization of seed overlap microRNA cotargeting associated with lupus pathogenesis

BACKGROUND: Combinatorial gene regulation by multiple microRNAs (miRNAs) is widespread and closely spaced target sites often act cooperatively to achieve stronger repression (“neighborhood” miRNA cotargeting). While miRNA cotarget sites are suggested to be more conserved and implicated in developmen...

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Detalles Bibliográficos
Autores principales: Kitai, Hiroki, Kato, Noritoshi, Ogami, Koichi, Komatsu, Shintaro, Watanabe, Yu, Yoshino, Seiko, Koshi, Eri, Tsubota, Shoma, Funahashi, Yoshio, Maeda, Takahiro, Furuhashi, Kazuhiro, Ishimoto, Takuji, Kosugi, Tomoki, Maruyama, Shoichi, Kadomatsu, Kenji, Suzuki, Hiroshi I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9650897/
https://www.ncbi.nlm.nih.gov/pubmed/36357926
http://dx.doi.org/10.1186/s12915-022-01447-4