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Analysis of mitochondrial dynamics and function in the retinal pigment epithelium by high-speed high-resolution live imaging

Mitochondrial dysfunction is strongly implicated in neurodegenerative diseases including age-related macular degeneration (AMD), which causes irreversible blindness in over 50 million older adults worldwide. A key site of insult in AMD is the retinal pigment epithelium (RPE), a monolayer of postmito...

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Detalles Bibliográficos
Autores principales: Tan, Li Xuan, Li, Jianlong, Germer, Colin J., Lakkaraju, Aparna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9651161/
https://www.ncbi.nlm.nih.gov/pubmed/36393836
http://dx.doi.org/10.3389/fcell.2022.1044672