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Enhanced recruitment of glutamate receptors underlies excitotoxicity of mitral cells in acute hyperammonemia

Hepatic encephalopathy (HE)–a major complication of liver disease–has been found to increase the risk of olfactory dysfunction, which may be attributed to elevated levels of ammonia/ammonium in the blood and cerebrospinal fluid. However, the cellular mechanisms underlying hyperammonemia-induced olfa...

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Detalles Bibliográficos
Autores principales: Li, Mingxian, Liu, Zhenqi, Lai, Ke, Liu, Hanwei, Gong, Lina, Shi, Haosong, Zhang, Weitian, Wang, Hui, Shi, Haibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9651449/
https://www.ncbi.nlm.nih.gov/pubmed/36385944
http://dx.doi.org/10.3389/fncel.2022.1002671