Endogenous and exogenous serotonin, but not sumatriptan, ameliorate seizures and neuroinflammation in the pentylenetetrazole-induced seizure model in rats

BACKGROUND: Epilepsy has neuropsychiatric comorbidities such as depression, bipolar disorder, and anxiety. Drugs that target epilepsy may also be useful for its neuropsychiatric comorbidities. OBJECTIVE: To investigate the effects of serotonergic modulation on pro-inflammatory cytokines and the seiz...

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Detalles Bibliográficos
Autores principales: Torun, Ibrahim Ethem, Kılınc, Yasemin Baranoglu, Kilinc, Erkan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academia Brasileira de Neurologia -ABNEURO 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9651504/
https://www.ncbi.nlm.nih.gov/pubmed/35239805
http://dx.doi.org/10.1590/0004-282X-ANP-2021-0101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9651504/
https://www.ncbi.nlm.nih.gov/pubmed/35239805
http://dx.doi.org/10.1590/0004-282X-ANP-2021-0101

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