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Induced inactivation of Wnt16 in young adult mice has no impact on osteoarthritis development

Osteoarthritis (OA) is a common disorder and a major cause of disability in the elderly population. WNT16 has been suggested to play important roles in joint formation, bone homeostasis and OA development, but the mechanism of action is not clear. Transgenic mice lacking Wnt16 expression (Wnt16(-/-)...

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Detalles Bibliográficos
Autores principales: Törnqvist, Anna E., Nilsson, Karin H., Li, Lei, Ohlsson, Claes, Movérare-Skrtic, Sofia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9651579/
https://www.ncbi.nlm.nih.gov/pubmed/36367882
http://dx.doi.org/10.1371/journal.pone.0277495